A research released in the journal Molecular Pharmacology in 2006 showed that cannabis contains a compound with two therapeutic qualities that can fully treat both the symptom and the main cause of Alzheimer’s disease. Another discovery that completely destroys the prevailing stereotype is that the use of marijuana “fries” the brain, leading to debilitating memory problems.
Researchers have found that the psychoactive component of marijuana, tetrahydrocannabinol (THC), “competitively inhibits the enzyme acetylcholinesterase (AChE) and inhibits AChE-induced amyloid peptide aggregation β-peptide (Aβ).
This is excellent news, considering that some drugs for the disease have serious side effects. Donepezil, for example, is very controversial because of its known association with seizures, probably due to its intrinsic neurotoxicity. In fact, a chemical of the same general chemical class as poison, insecticides, and chemical warfare agents, such as nerve gas, is used to develop this drug. With cannabis, you wouldn’t have to worry about this, especially if you grew it yourself.
THC, as the researchers point out, prevents the formation of plaques in the brain and suggests that it “may have a direct influence on the pathology of Alzheimer’s disease,” as the researchers have pointed out. They concluded that “THC is a substantially superior aggregator inhibitor of Aβ compared to drugs currently prescribed and approved for the purpose of treating Alzheimer’s disease, and this study provides a previously unknown molecular mechanism by which cannabinoid molecules may have a direct influence on the progression of this disabling disease.
As the study shows:
THC is a significantly more effective inhibitor of AChE-induced deposition of Aβ than the drugs Donepezil and Tacrin, which are approved for the treatment of Alzheimer’s disease and which reduced the aggregation of Aβ by only 22% and 7% respectively to twice the concentration used in our studies7. 7 Therefore, AChE inhibitors such as THC and its analogs may offer better therapy for Alzheimer’s disease by increasing acetylcholine levels, preventing the breakdown of neurotransmitters, and reducing the aggregation of Aβ, while treating the symptoms and progression of Alzheimer’s disease.
This is quite remarkable, and one more reason to grow your own marijuana. In Canada, you can do this simply by applying for your medical marijuana card through the CWDMA program in Canada.
This study is several years old, but even recent research has shown that in Alzheimer’s disease, the compounds contained in cannabis, such as THC and CBD, can actually improve memory and even prevent some of the symptoms of Alzheimer’s disease. The latest findings were presented last year at the annual meeting of the German Society for Neuroscience, the world’s largest source of information on brain research and health.
The new findings showed that treatment of mice with Alzheimer’s disease using the psychoactive substance found in marijuana improves memory and reduces neuronal loss, suggesting a possible therapy for the human disease.
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