Home Mindfulness & Peace According To Studies, Anti-Inflammatories Could Help Reduce Depression.

According To Studies, Anti-Inflammatories Could Help Reduce Depression.

In regards to this kind of thing Science Daily wrote as follows:

An emerging body of evidence suggests that inflammation contributes to the development of major depression, but the results of clinical trials using various anti-inflammatory agents to treat the condition have proved inconclusive.

The researchers, therefore, set out to review the available evidence and pool the data to see if anti-inflammatory agents work better than dummy (placebo) treatment either alone or when used as add-on therapy to standard antidepressant treatment.

Anti-inflammatory agents included: non-steroidal anti-inflammatory drugs (NSAIDs); omega 3 fatty acids; drugs that curb production of inflammatory chemicals (cytokine inhibitors); statins; steroids; antibiotics (minocycline’s); a drug used to treat sleep disorders (modafinil); and N-acetyl cysteine, known as NAC, and used to loosen the excess phlegm of cystic fibrosis and COPD and also taken as an antioxidant supplement.

The researchers trawled research databases to find suitable studies published up to January 2019. They found 30 relevant randomized controlled trials, involving 1610 people, which reported changes in depression scales. They pooled the data from 26 of these studies.

The pooled data analysis suggested that anti-inflammatory agents were better than placebo and enhanced the effects of standard antidepressant treatment.

These agents were 52% more effective in reducing symptom severity, overall, and 79% more effective in eliminating symptoms than placebo, as measured by an average fall in depression scales of 55.

More detailed analysis indicated that NSAIDs, omega 3 fatty acids, statins, and minocycline’s were the most effective at reducing major depressive symptoms compared with placebo.

And the effects were even greater when one or other of these agents was added to standard antidepressant treatment.”

So Would you think about using anti-inflammatory to reduce the symptoms of depression? There are no side effects of using this method, but only a few people struggled with minor side effects such as stomach pain, heartburn, or minor kidney issues.

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